SR 9009 Capsule

SR-9009 Stenabolic

The SR 9009 capsule is made from 99% pure SR 9009 powder, Also known as Stenabolic, SR-9009 is a synthetic small molecule developed by the team of Thomas Burris, Professor of Molecular Medicine at The Scripps Research Institute. It is a selective agonist of the REV-ERB nuclear receptor, affecting energy metabolism, inflammation, and circadian rhythms by targeting gene regulatory networks associated with the circadian clock. SR-9009 was initially developed to study the relationship between circadian rhythms and metabolic diseases. It later garnered widespread attention in fitness and exercise research due to its potential to improve endurance, reduce fat, and improve metabolism in animal studies. Mechanistically, SR-9009 activates REV-ERB / , downregulating the expression of genes involved in lipogenesis, gluconeogenesis, and energy storage, while upregulating genes involved in energy expenditure, thereby promoting greater energy consumption as fat. Animal studies have shown that SR-9009 can increase mitochondrial number and activity, increase basal metabolic rate, and improve blood lipid and glucose levels. Therefore, it is often used in scientific research to study metabolic syndrome, obesity, diabetes and cardiovascular disease models. If you need SR 9009, Xi'an Sonwu can supply it. Xi'an Sonwu is looking forward to hearing from you.

HPLC Of SR 9009

SR 9009 price

Xi'an Sonwu Biotech Co., Ltd. has rich experience in global trade and the health industry. Insisting on faith-based and quality-first principles is our company's guiding principle. We strictly control product quality, which means our selection process begins with raw materials. Additionally, we handle every detail and minimize costs to the maximum, allowing our customers to obtain cost-effective products. Based on this, customers have provided a lot of positive feedback about our products. So look for Xi'an Sonwu Biotech Co., Ltd. when buying SR 9009.

Xi'an Sonwu ensures product quality and can provide samples upon request. Here is the quantity.

Xi'an Sonwu can supply high-quality SR 9009 capsules, including their powder and liquid.

Customers can customise the capsules they want. The items below can be supplied.

What Is The Effect of SR9009

SR9009 (Stenabolic) is a synthetic compound that acts as a REV-ERB / agonist, which means it activates these nuclear receptors involved in regulating the circadian clock and metabolism. Its effects have been studied mostly in animal models and in vitro, with some key findings:

1. Metabolic Effects

Increased energy expenditure: SR9009 boosts basal metabolism by upregulating genes involved in mitochondrial function and energy consumption.

Reduced fat mass: Animal studies show it can decrease fat accumulation and improve body composition.

Improved glucose metabolism: Can lower blood glucose and improve insulin sensitivity in metabolic disorder models.

2. Exercise and Endurance

Enhanced endurance: In mice, SR9009 increases exercise capacity by enhancing skeletal muscle mitochondria and oxidative metabolism.

Muscle efficiency: Promotes more efficient energy utilization in muscles during activity.

3. Anti-inflammatory Effects

Decreases inflammation: Can suppress inflammatory gene expression in liver and other tissues, potentially protecting against metabolic inflammation.

4. Circadian Rhythm Regulation

Modulates the biological clock: By activating REV-ERB / , SR9009 influences circadian gene expression, which can indirectly affect metabolism, sleep-wake cycles, and hormonal rhythms.

SR 9009 Mechanism of Action

SR9009 is a synthetic agonist of the REV-ERB nuclear receptors (REV-ERB and REV-ERB ). These receptors are transcription factors that play key roles in regulating circadian rhythm, metabolism, and inflammation. Here's a detailed breakdown:

1. REV-ERB Activation

SR9009 binds selectively to REV-ERB / , enhancing their activity.

REV-ERBs normally act as transcriptional repressors, inhibiting the expression of target genes involved in lipid metabolism, glucose production, and the circadian clock.

By activating REV-ERB, SR9009 suppresses genes that promote fat storage and gluconeogenesis while promoting genes that increase energy expenditure.

2. Effects on Circadian Rhythm

REV-ERB / are integral to the circadian clock feedback loop.

SR9009 shifts the expression of circadian genes, which modulates daily patterns of metabolism, hormone release, and energy use.

3. Metabolic Effects

Increased mitochondrial activity → boosts fatty acid oxidation and basal metabolic rate.

Reduced lipid synthesis → lowers fat accumulation.

Improved glucose homeostasis → reduces blood glucose levels in animal studies.

4. Anti-inflammatory Effects

SR9009 reduces the expression of inflammatory genes in liver, muscle, and other tissues.

This contributes to protection against metabolic inflammation.

Does SR9009 Affect Sleep

Yes, SR9009 can potentially affect sleep, though the data mainly come from animal studies. This effect is linked to its mechanism of action on REV-ERB / nuclear receptors, which are key regulators of the circadian rhythm.

How SR9009 May Affect Sleep

1. Circadian Rhythm Modulation

REV-ERB / are part of the biological clock that regulates sleep-wake cycles, hormone secretion, and metabolism.

SR9009, as a REV-ERB agonist, can shift the timing of circadian gene expression.

In mice, activation of REV-ERB by SR9009 alters activity patterns, sometimes leading to changes in rest and active periods.

2. Indirect Metabolic Effects

By increasing energy expenditure and mitochondrial activity, SR9009 may increase alertness or daytime activity in animals.

This could potentially interfere with normal sleep onset if similar effects occur in humans.

3.. Lack of Human Data

No clinical studies have been done in humans, so the sleep-related effects in humans are unknown.

Any speculation is extrapolated from circadian biology and preclinical models.

What Does SR9009 Do To The Liver

SR9009 primarily acts as a REV-ERB / agonist, and these nuclear receptors are expressed in the liver, where they regulate metabolism, lipid synthesis, and inflammation. Most data come from animal studies, as SR9009 is not approved for human use.

1. Effects on Liver Metabolism

Animal studies show SR9009 suppresses genes involved in lipogenesis (fat synthesis) and promotes fatty acid oxidation, which can reduce liver fat.

SR9009 decreases gluconeogenesis (glucose production by the liver), helping lower blood glucose in animal models.

Increases liver mitochondrial function, enhancing energy metabolism.

2. Anti-inflammatory Effects

SR9009 downregulates inflammatory gene expression in the liver, which may protect against metabolic liver disorders.

3. Potential Risks

Short-term animal studies show SR9009 is generally tolerated, but long-term liver safety in humans is unknown.

High doses or chronic exposure could theoretically stress the liver, as with many metabolic modulators.

1. Xi'an Sonwu has a factory with sufficient stock. In addition, Xi'an Sonwu has a clean and tidy production department with advanced equipment. Under the company's leadership, researchers continue to develop new products to meet customers' needs.

2. Xi'an Sonwu has advanced testing equipment and professional testing personnel, all of which show that Xi'an Sonwu aims to provide accurate and effective data and good service.

In addition to guaranteeing product quality, the most vital aspect is ensuring that clients receive the goods smoothly. So, Xi'an Sonwu supplies all kinds of couriers according to different needs.

1. How to inquire?

We can be reached by phone, email, or social media.

2. How do you guarantee the quality of products?

Each batch must be tested, and a COA can be supplied to customers. Additionally, all the products pass the test: HPLC, UV, GC, TLC, etc. We also cooperate with third parties, such as SGS.

3. How do you pack and store?

Pack: Use sealed export-grade drums and vacuum-sealed foil packaging, or pack the goods according to customers' needs.

Storage: Store it in a dry, cool place, away from sunlight.

If you want to know about the SR 9009 capsule, you can contact Xi'an Sonwu. Click the email, and you'll receive high-quality stenabolic capsule.

sales@sonwu.com

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